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Ingredient · Flavor

Monosodium Glutamate

Mixed · 6/10, higher is cleaner

E-number E621

How we reached this

Long-standing safety record; sensitivity in some subjects but not allergic reaction. Demonized historically without strong evidence.

Sources · 1

Regulatory position

European UnionPermitted (E621)
United StatesGRAS (21 CFR 182.1)
NotesLong-standing safety record; sensitivity in some subjects but not allergic reaction. | Long-standing safety record; sensitivity in some subjects but not allergic reaction.

Also listed as

E621MSG

Products containing this · 11

About this rating

Ratings run 1–10, higher is cleaner, and are set editorially against the sources above — see the methodology page for how an ingredient rating becomes part of a product score. Last reviewed 2026-05-23.